Sebastiano Rolli studied Chamber Music and Composition at the Conservatory of Parma and Milan and Musical drama with Marcello Conati; he started his career as a conductor at a very young age, distinguishing as one of the most exciting performers of his generation.

In past years he started collaborations with many theatres and orchestras conducting, among the others: Il Trovatore, La Traviata, Rigoletto, Aida, Attila, Nabucco, Il Barbiere di Siviglia, Le Nozze di Figaro, Il Tabarro, Cavalleria rusticana.

In the past seasons he conducted: Macbeth at the Slovak National Opera in Bratislava; Maria Stuarda at the Teatro Sociale in Rovigo, at the Teatro Donizetti in Bergamo and at the Teatro Filarmonico in Verona ; Il Trovatore and Maria di Rudenz at the Teatro Donizetti in Bergamo; Falstaff at the Teatro Verdi in Busseto for the Festival Verdi; I Puritani at the Slovak National Opera in Bratislava; Torquato Tasso at the Teatro Donizetti in Bergamo; Gianni Schicchi and Suor Angelica in Tirana; a recital at the Concert Hall in Dublin along with Juan Diego Florez; Anna Bolena at the Opera in Tenerife; Faurè’s Requiem, Verdi’s Quattro pezzi sacri and Die Lustige Witwe  at the  Teatro Lirico in Cagliari Cagliari; La Cenerentola and Pierino e il lupo at the Filarmonico in Verona;  Lucia di Lammermoor at the Regio in Parma and in Savon; a tour with Juan Diego Florez in Mexico and Perù and La Sonnambula in Catania.

Most recently he conducted: Verdi’s Requiem in Madesana with the Teatro Regio of Parma; Donizetti’s Rosmonda d'Inghilterra in Bergamo and in Firenze; Bellini’s La straniera in Catania; L’Italiana in Algeri with the Opera of Florence in Oman; Norma in Tenerife; La Traviata in Florence, in Parma, In Busseto and in Bolzano; Donizetti’s Roberto Devereux in Parma; Nabucco for the Israeli Opera; La Sonnambula in Florence; Il Trovatore for Rete Lirica delle Marche and in Tirana; Un ballo in maschera in Parma; La Traviata in Florence, Pagliacci in Sassari; Il Barbiere di Siviglia in Fribourg; Il Maestro di Cappella ad Ancona.

Among his numerous publications, two critical studies on "Giuseppe Verdi. The masters of melodramma "Giuseppe Di Stefano. His characters" - Azzali Publishers. He is regularly invited by musical institutions and conservatoires to keep masters in-depth interpretation of Verdi or choral music. He was professor of interpretation of the score and vocal diction for singers in the courses "Mythos" of the "Fondazione Arturo Toscanini" and "Fondazione Teatro Alla Scala" in Milan.